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Neu(Phospho Thr686) Polyclonal Antibody, 50ul Adenovirus Packaging the adaptor protein Shc and

SKU: 42545227394

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Neu(Phospho Thr686) Polyclonal Antibody, 50ul Adenovirus Packaging the adaptor protein Shc andThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated

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Description

the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated

The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al

Transcripts at this locus may also undergo A to I editing

alternative products:Experimental confirmation may be lacking for some isoforms|Catalytic activity:Hydrolysis of alkylated DNA| releasing 3-methyladenine| 3-methylguanine| 7-methylguanine and 7-methyladenine

and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD)

Neu(Phospho Thr686) Polyclonal Antibody, 50ul Adenovirus Packaging the adaptor protein Shc andThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated

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