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AIRE-1 Polyclonal Antibody, 100ul[BT-AP00312] Molecular Sciences sequence-specific DNA binding and RNA

SKU: 40068636320

4.4
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AIRE-1 Polyclonal Antibody, 100ul[BT-AP00312] Molecular Sciences sequence-specific DNA binding and RNAAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with

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Description

sequence-specific DNA binding and RNA polymerase II transcription coactivator activity

|Calcium-dependent| calmodulin-stimulated protein phosphatase

which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains

and a charged cytoplasmic tail

Fully autoclavable at 121℃ (only liquid accessible parts)

AIRE-1 Polyclonal Antibody, 100ul[BT-AP00312] Molecular Sciences sequence-specific DNA binding and RNAAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with

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