TRIM3 Polyclonal Antibody, 100ul Nucleic Acid Amplification The protein encoded by PAK3

The protein encoded by PAK3 is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like P21

alpha-type (AC Q9Y4C0) and beta-type (shown here)

The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits| generated by proteolytic cleavage of a single-chain precursor

It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation

Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets

TRIM3 Polyclonal Antibody, 100ul Nucleic Acid Amplification The protein encoded by PAK3The tripartite motif containing 3 encoded by TRIM3 is a member of the tripartite motif (TRIM) family, also called the 'RING B box coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class