GRK 2(Phospho Ser685) Polyclonal Antibody, 20ul Sampling Tubes This gene encodes a member

This gene encodes a member of the highly conserved cyclin C subfamily

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calcium/calmodulin- dependent protein kinase II

Alternatively spliced transcript variants containing different 5' UTRs

is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988)

GRK 2(Phospho Ser685) Polyclonal Antibody, 20ul Sampling Tubes This gene encodes a memberThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.