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Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The encoded protein also appears

SKU: 37830212343

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Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The encoded protein also appearsThe product of OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso peptidase, and cleaves ubiquitin from branched poly ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.

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Description

The encoded protein also appears to be important for stem cell proliferation

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The palladin

Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior

The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies

Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The encoded protein also appearsThe product of OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso peptidase, and cleaves ubiquitin from branched poly ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.

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