IRF-3 Polyclonal Antibody, 50ul[BT-AP04627] Antibody Development There are six pseudogenes of

There are six pseudogenes of this gene found on chromosomes 2

GSDMC is a Protein Coding gene

Belongs to the small leucine-rich proteoglycan (SLRP) family

Probably involved in anxiety and depression

Defects in this gene are a cause of several syndromes

IRF-3 Polyclonal Antibody, 50ul[BT-AP04627] Antibody Development There are six pseudogenes ofIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed