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LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences This gene is similar to

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LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences This gene is similar toSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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Description

This gene is similar to the Sem5 gene of C

but appear to have divergent biological functions

Cyclin dependent kinase 11B encoded by CDK11B can be cleaved by caspases and may play a role in cell apoptosis

and a key role in cardiovascular homeostasis

LIN54 is a component of the LIN| or DREAM| complex| an essential regulator of cell cycle genes (Schmit et al

LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences This gene is similar toSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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