Mouse Glycogen Synthase Kinase-3 Beta, GSK3B ELISA Kit, 96T Purification Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different protein isoforms have been described

This protein is activated by PI3-kinase

ALLELE C*12:02: Presents CMV epitope derived from UL83 (VAFTSHEHF) to CD8-positive T cells

This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails

The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene

Mouse Glycogen Synthase Kinase-3 Beta, GSK3B ELISA Kit, 96T Purification Alternatively spliced transcript variants encodingConstitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen Synthase (GYS1 or GYS2), EIF2B, CTNNB1 beta catenin, APC, AXIN1, DPYSL2 CRMP2, JUN, NFATC1 NFATC, MAPT TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to