GPTC8 Polyclonal Antibody, 50ul Molecular Biology and Brooke-Spiegler syndrome

and Brooke-Spiegler syndrome

The type VII collagen fibril

and neonatal respiratory distress

One isoform lacks the intermembrane region and is secreted outside the cell

Dok-5 and Dok-6 are more similar to each other than to the other Dok family members

GPTC8 Polyclonal Antibody, 50ul Molecular Biology and Brooke-Spiegler syndromeThe protein encoded by this gene contains an RNA processing domain, a zinc finger domain, a lysine rich region and a serine rich region. A mutation in the serine rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610). Alternative splicing results in multiple transcript variants encoding different isoforms.