AGTR2 Polyclonal Antibody, 50ul NGS Oligos chemokine (C-C motif) ligand 14

chemokine (C-C motif) ligand 14

(Tsuneoka et al

Studies of the mouse and chick homologs revealed roles in midbrain and limb development

Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy

hydrophobic C-terminal domain with a steroid substrate binding site

AGTR2 Polyclonal Antibody, 50ul NGS Oligos chemokine (C-C motif) ligand 14The protein encoded by this gene belongs to the G protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology.