MLH1 Polyclonal Antibody, 20ul Rotator A subset of patients with
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MLH1 Polyclonal Antibody, 20ul Rotator A subset of patients withMLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full length natures have not
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