Histone H3 Polyclonal Antibody, 100ul[BT-AP04080] Cell Culture & Maintenance Chloride intracellular channel 4 (CLIC4)

Chloride intracellular channel 4 (CLIC4) protein

SSR3 and mutant SOD1 that lead to motor neuron death in FALS

Among its related pathways are Endocytosis and Notch Signaling Pathways

Epigenetic silencing of this gene has been observed in gliomas

Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains

Histone H3 Polyclonal Antibody, 100ul[BT-AP04080] Cell Culture & Maintenance Chloride intracellular channel 4 (CLIC4)Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin