CdGAP(Phospho Thr789) Polyclonal Antibody, 20ul Cell Screening and Imaging Defects in this gene are

Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL)

SEMA4A encodes a member of the semaphorin family of soluble and transmembrane proteins

where it is involved in transcriptional regulation

This gene product appears to form only homodimers

Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements

CdGAP(Phospho Thr789) Polyclonal Antibody, 20ul Cell Screening and Imaging Defects in this gene areThis gene encodes a GTPase activating protein (GAP). A variety of cellular processes are regulated by Rho GTPases which cycle between an inactive form bound to GDP and an active form bound to GTP. This cycling between inactive and active forms is regulated by guanine nucleotide exchange factors and GAPs. The encoded protein is a GAP shown to regulate two GTPases involved in protein trafficking and cell growth.