PIGR Polyclonal Antibody, 50ul Gloves Mutations in CBX2 are also

Mutations in CBX2 are also associated with gonadal dysgenesis in humans

can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis

This protein also interacts with and is acetylated by MCM3AP

The protein can bind to the HIV-1 TAR mRNA

Alternative splicing results in transcript variants

PIGR Polyclonal Antibody, 50ul Gloves Mutations in CBX2 are alsoThis gene is a member of the immunoglobulin superfamily. The encoded poly Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.