Phospho-APC (S2054) Polyclonal Antibody, 100ul Cell Function Analysis possibly as a result of

possibly as a result of compromised regulatory T cell recruitment

a dimerization domain

Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma

TMEM145 (transmembrane protein 145) is a 493 amino acid protein encoded by a gene mapping to human chromosome 19

This protein may also play a role in oncogenesis

Phospho-APC (S2054) Polyclonal Antibody, 100ul Cell Function Analysis possibly as a result ofAPC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a small region designated the