GATA-5 Monoclonal Antibody, 50ul Fluorescent Staining GDF5 encodes a secreted ligand

GDF5 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

This protein is localized in the nucleus and contains an E1A-type zinc finger domain

Preferential methylation of this gene's promoter is associated with advanced-stage neuroblastoma tumors

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6-biphosphatase activity that catalyzes the degradation of fructose-2

GATA-5 Monoclonal Antibody, 50ul Fluorescent Staining GDF5 encodes a secreted ligandThe protein encoded by this gene is a transcription factor that contains two GATA type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor 1alpha (HNF 1alpha), and this interaction is essential for cooperative activation of the intestinal lactase phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.