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LZTR1 Polyclonal Antibody, 20ul Electronic Pipette Fibroblast cells from CAID patients

SKU: 21847507770

4.3
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LZTR1 Polyclonal Antibody, 20ul Electronic Pipette Fibroblast cells from CAID patientsThis gene encodes a member of the BTB kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.

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Description

Fibroblast cells from CAID patients exhibited both increased cell proliferation and higher rates of senescence

The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene| RELA

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Alternate splicing results in multiple transcript variants encoding different isoforms

Upon activation of the alternative pathway

LZTR1 Polyclonal Antibody, 20ul Electronic Pipette Fibroblast cells from CAID patientsThis gene encodes a member of the BTB kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.

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