CHOP mouse Monoclonal Antibody(1E1), 100ul Cell Function Analysis TNFRSF10B/TRAILR2

TNFRSF10B/TRAILR2

Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion

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which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix

which encode the same protein

CHOP mouse Monoclonal Antibody(1E1), 100ul Cell Function Analysis TNFRSF10B/TRAILR2This gene encodes a member of the CCAAT enhancer binding protein (C EBP) family of transcription factors. The protein functions as a dominant negative inhibitor by forming heterodimers with other C EBP members, such as C EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene