PAR-3 Polyclonal Antibody, 50ul Multiplex Immunoassays Mutations in MTR have been

Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G

PER2 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL

May be involved in pre-mRNA splicing

Alternative splicing of this gene results in four transcript variants

Related pseudogenes have been identified on chromosomes 8| 15 and 19

PAR-3 Polyclonal Antibody, 50ul Multiplex Immunoassays Mutations in MTR have beenF2RL2 encodes a member of the protease activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein coupled cell surface receptor family. The coagulation factor II thrombin receptor like 2 acts as a cofactor in the thrombin mediated cleavage and activation of the protease activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple