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VASP(Phospho Thr278) Polyclonal Antibody, 50ul Adeno-associated Virus Packaging PIM1 is expressed primarily in

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VASP(Phospho Thr278) Polyclonal Antibody, 50ul Adeno-associated Virus Packaging PIM1 is expressed primarily inVasodilator stimulated phosphoprotein (VASP) is a member of the Ena VASP protein family. Ena VASP family members contain an EHV1 N terminal domain that binds proteins containing E DFPPPPXD E motifs and targets Ena VASP proteins to focal adhesions. In the mid region of the protein, family members have a proline rich domain that binds SH3 and WW domain containing proteins. Their C terminal EVH2 domain mediates tetramerization and binds both G and F

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Description

PIM1 is expressed primarily in B-lymphoid and myeloid cell lines

A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family

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Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis

VASP(Phospho Thr278) Polyclonal Antibody, 50ul Adeno-associated Virus Packaging PIM1 is expressed primarily inVasodilator stimulated phosphoprotein (VASP) is a member of the Ena VASP protein family. Ena VASP family members contain an EHV1 N terminal domain that binds proteins containing E DFPPPPXD E motifs and targets Ena VASP proteins to focal adhesions. In the mid region of the protein, family members have a proline rich domain that binds SH3 and WW domain containing proteins. Their C terminal EVH2 domain mediates tetramerization and binds both G and F

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