IL-10R Alpha Polyclonal Antibody, 100ul[BT-AP04431] Rotator MAD2L1 is a component of

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate

Several transcript variants encoding different isoforms have been found for ATG16L1

Both calcium/calmodulin and protein phosphorylation mechanisms control its activity

and it complements a transformation-defective Myc Box II mutant

This protein also plays a role in cell proliferation

IL-10R Alpha Polyclonal Antibody, 100ul[BT-AP04431] Rotator MAD2L1 is a component ofInterleukin 10 receptor subunit alpha encoded by IL10RA is a receptor for interleukin 10. Interleukin 10 receptor subunit alpha is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate 2 PI 3 kinase AKT pathway.