MDM2 Polyclonal Antibody, 20ul[BT-AP05301] Purification and this interaction may play

and this interaction may play a role in ovulation and fertilization

and may play a catalytic role in the function of the SMN complex on RNPs

but particularly in cells of the immune and nervous systems

Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes

kidney and muscle

MDM2 Polyclonal Antibody, 20ul[BT-AP05301] Purification and this interaction may playMDM2 encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many