Cables1 Polyclonal Antibody, 100ul Micro Centrifuge Tubes These proteins bind and activate

These proteins bind and activate PDGF receptor tyrosine kinases

upstream open reading frame which is located between the GUG and the first AUG start codons

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In spite of the gene family name similarity

This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE)

Cables1 Polyclonal Antibody, 100ul Micro Centrifuge Tubes These proteins bind and activateCABLES1 encodes a protein (Cdk5 and Abl enzyme substrate 1) involved in regulation of the cell cycle through interactions with several cyclin dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127). Multiple transcript variants encoding