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NOD1 Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries Variations in this gene have

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NOD1 Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries Variations in this gene haveThis gene encodes a member of the NOD (nucleotide binding oligomerization domain) family. This member is a cytosolic protein. It contains an N terminal caspase recruitment domain (CARD) a centrally located nucleotide binding domain (NBD) and 10 tandem leucine rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling LRRs participate in protein protein interactions and mutations in the NBD may affect the process of

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Description

Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS)

suggesting a role of pyruvate kinase

DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events

It is also reported that the this protein functions as a demethylase to activate transcription| as DNA methylation causes gene silencing

Among its related pathways are Gene Expression

NOD1 Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries Variations in this gene haveThis gene encodes a member of the NOD (nucleotide binding oligomerization domain) family. This member is a cytosolic protein. It contains an N terminal caspase recruitment domain (CARD) a centrally located nucleotide binding domain (NBD) and 10 tandem leucine rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling LRRs participate in protein protein interactions and mutations in the NBD may affect the process of

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