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SFRP1 Polyclonal Antibody, 20ul Protein Expression This gene encodes a member

SKU: 11794240736

4.1
PLN111.00 PLN151.00

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SFRP1 Polyclonal Antibody, 20ul Protein Expression This gene encodes a memberThis gene encodes a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

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Description

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET

Mutations in this gene have been associated with geleophysic dysplasia

It is highly expressed in adrenal gland

Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity)

Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase

SFRP1 Polyclonal Antibody, 20ul Protein Expression This gene encodes a memberThis gene encodes a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

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