SirT1(Phospho-Ser27) Rabbit Polyclonal Antibody, 50ul Proteases The Transcription elongation factor A

The Transcription elongation factor A protein-like 1 is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region

This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death

The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+

and it contributes to spinal sensitization and neuropathic pain states

GO annotations related to this gene include ligase activity and ubiquitin protein ligase activity

SirT1(Phospho-Ser27) Rabbit Polyclonal Antibody, 50ul Proteases The Transcription elongation factor AThis gene encodes a member of the sirtuin family of proteins homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular