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DPYD Polyclonal Antibody, 100ul Bacterial Expression Mutations in this gene are

SKU: 10340361980

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DPYD Polyclonal Antibody, 100ul Bacterial Expression Mutations in this gene areDihydropyrimidine dehydrogenase [NADP(+)] encoded by DPYD is a pyrimidine catabolic enzyme and the initial and rate limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine uraciluria and an increased risk of toxicity in cancer patients receiving 5 fluorouracil chemotherapy. Two transcript variants encoding

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Description

Mutations in this gene are associated with Cenani-Lenz syndrome

with alphanumeric markers to facilitate identification and marking

This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes

the protein associates with spindle microtubules near the centrosomes

subunit:Binds DNA as a dimer

DPYD Polyclonal Antibody, 100ul Bacterial Expression Mutations in this gene areDihydropyrimidine dehydrogenase [NADP(+)] encoded by DPYD is a pyrimidine catabolic enzyme and the initial and rate limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine uraciluria and an increased risk of toxicity in cancer patients receiving 5 fluorouracil chemotherapy. Two transcript variants encoding

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