Histone H3 (Di Methyl Lys79) Polyclonal Antibody, 20ul Vessels in particular the anaplastic lymphoma

in particular the anaplastic lymphoma kinase gene on chromosome 2

A related pseudogene has been identified on chromosome 10

interleukin 3 regulated encoded by NFIL3 is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters

it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway

This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors

Histone H3 (Di Methyl Lys79) Polyclonal Antibody, 20ul Vessels in particular the anaplastic lymphomaHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin